Retention of embryonic features by an adult neuronal system capable of plasticity: polysialylated neural cell adhesion molecule in the hypothalamo-neurohypophysial system.
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چکیده
منابع مشابه
Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule.
Many factors have been shown to promote myelination, but few have been shown to be inhibitory. Here, we show that polysialylated-neural cell adhesion molecule (PSA-NCAM) can negatively regulate myelin formation. During development, PSA-NCAM is first expressed on all growing fibers; then, axonal expression is down-regulated and myelin deposition occurs only on PSA-NCAM-negative axons. Similarly,...
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Background:The polysialylated neural cell adhesion molecule (PSA-NCAM) is expressed in developing brain. Fetal brain damage is caused by different conditions such as seizure and hypoxia. The present study was designed to investigate the effect of maternal seizures on the number of PSA-NCAM positive cells in pup's hippocampus. Methods: Female Wistar rats were divided into four groups: (a) kindle...
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چکیده ندارد.
15 صفحه اولAn Examination of the Hypothalamo-neurohypophysial System of the Rat: Restoration of the Vasopressinergic System
The hypothalamo-neurohypophysial model has been studied for many years. note , when the axons of the magnocellular, peptidergic neurons of the supraoptic nucleus (SON) and paraventricular nucleus (PVN) are transected or crushed, varing degrees polydipsia and polyuria ensue as the result of measurable losses of vasopressin (A VP) within the organism s circulation. Following insult, these hypotha...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1991
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.88.13.5494